Prime™ NAD+

Frequently Asked Questions

• How should I take Prime NAD+?

  Adults, take 2 capsules every morning with or without food. This supplement is meant to be taken only once a day.

• Is there anyone who should not take this product?

  If you are currently using any prescription drugs or have an ongoing medical condition, consult your healthcare provider before using this product. Do not take this product if you are pregnant or breastfeeding.

• What are the two factors that play into the continuous replenishment of NAD+ in the cells?

  The consumption and synthesis of NAD+ are two factors that play into the replenishment or concentration levels of NAD+ within the cells. There are three pathways that are responsible for helping to maintain this balance, known as the Preiss-Handler pathway, de novo biosynthesis pathway and the salvage pathway. Each of these pathways works in different ways to help the precursor NR and other NAD+ precursors convert into NAD+ for the body’s cells. The NAD+ precursor NR is specifically linked to the salvage pathway.

• What is NAD+/NADH redox ratio?

  NAD+ is recognized as the oxidized form of nicotinamide adenine dinucleotides whereas NADH is the reduced form. Overall, the NAD+/NADH redox ratio explains how well the cells are creating energy or ATP, portraying the current condition of cellular health and metabolism. NAD+-depleting lifestyles can negatively impact this ratio, throwing it off balance and leading to a decreased ratio which is also associated with age. Consuming more NAD+ precursors which help support levels of NAD+ is effective for helping to maintain a healthy balance of this ratio.

• What can deplete NAD+ levels in the body other than aging?

  Regardless of age, rough lifestyle habits can contribute to the increased need of NAD+. Smoking, alcohol consumption, lack of exercise, being overweight, insufficient sleep and eating an unhealthy diet are all factors that can lead to NAD+

• What are NAD+ precursors?

  Various sources of vitamin B3, including nicotinamide riboside (NR), nicotinic acid (NA), nicotinamide (NAM), nicotinamide mononucleotide (NMN), and tryptophan (Trp), are known as precursors of NAD+, meaning they influence or help build upon the production of NAD+.

• What is the half-life of pterostilbene in comparison to resveratrol?

  Pterostilbene has a much longer half-life (105 minutes) than resveratrol (14 minutes), meaning that pterostilbene is actively working in your system for a longer time.

• What are other ways you can promote sirtuin activity?

  Sirtuins are special molecules that are associated with supporting the cells’ lifespan. In addition to NR and pterostilbene, the youthful, antioxidant-rich molecule, sirtuin activity can also be promoted by supplementing with resveratrol and curcumin. Exercise and a decrease in caloric intake have also been shown to be effective ways to naturally increase the activity of sirtuins.

• What are telomeres?

  Telomeres are genome-protective caps that are located at the ends of chromosomes and indicate the age or suggested lifespan of a cell, in which the longer the telomere in length, the better. Telomeres are like the clear coating at the end of the shoelace string that keeps the lace from fraying; each time your cells divide, the chromosomal telomeres become shorter. Where maintaining healthy NAD+ production promotes healthy sirtuin activity, healthy sirtuin activity helps support the regulation of telomeres. Evidence shows that shorter telomeres contain lower NAD+ Just as NAD+ levels decrease with age, telomeres naturally shorten with age and both are correlated with the health of the cells and their ability to support the body’s cellular regeneration process.

• What is the goal of Prime NAD+?

  While all our Prime products are crafted to promote healthy aging at every level (including vision health, cardiovascular health, joint or hormone support), Prime NAD+ was specifically formulated to help you maintain a healthy reservoir of the youthful NAD+ molecule to help support cellular health function.